Understanding Desmoid Tumors: Causes, Symptoms, Diagnosis, and Treatment
Desmoid tumors, also known as aggressive fibromatosis, are rare, noncancerous (benign) growths that develop from fibroblasts — the connective tissue cells responsible for healing and structural support in the body. Although they do not metastasize (spread to other organs), desmoid tumors can be locally aggressive, invading nearby muscles, nerves, and organs, leading to pain and functional impairment.
Because of their unpredictable behavior — sometimes growing rapidly, sometimes remaining stable for years — desmoid tumors require a careful, individualized treatment approach.
What Are Desmoid Tumors?
Desmoid tumors arise from fibrous connective tissue and can occur anywhere in the body, but they most commonly appear in the:
Abdomen (especially the abdominal wall)
Shoulders and upper arms
Thighs
Trunk
Mesentery (tissue that connects the intestines)
While they are benign, they can cause serious complications by pressing on nearby organs, blood vessels, or nerves.